In this BLOSSOMS video lesson, three young scientists and one young engineer from MIT’s Koch Institute for Integrative Cancer Research speak directly to high school students about their own high school and college paths leading into the healthcare field. The four interviewees in this lesson provide compelling testimonies on the rewarding nature of their work, while at the same time dispelling stereotypes about the STEM field and encouraging women and minorities to feel welcomed into it. After each of the four interviews, students are invited to participate in a brief reflective activity related to possible STEM careers. Teachers using this lesson can present the entire 28-minute video at once, which together with the brief activities would fill a 50-minute class period. Alternatively, a teacher could choose to present each of the four interviews individually. Along with this lesson on the BLOSSOMS website, teachers and students will find a list of Additional Online Resources identifying organizations across the country where students can find opportunities to learn more about STEM careers. We also encourage teachers and students to contact your local higher education institutions, research hospitals and businesses to inquire about their STEM outreach programs.